Hello I'M

Shakila Silva

B.Sc. (Honors) in Chemistry

"Aims to contribute to the development of innovative and sustainable solutions in the area of chemistry by pursuing higher education. Through rigorous academic study, research experience, collaboration, and finally aim to become a proficient chemist capable of addressing complex scientific challenges and making meaningful contributions to scientific knowledge and advancements. "

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About Me

Education

B.Sc. (Honors) in Chemistry (2017-2022)
Second Class (Lower Division) with a 3.1 GPA Rajarata University of Sri Lanka.

Research Experience

Undergraduate research on “Acetylated cassava starch nanoparticles for targeted anticancer drug delivery.”
In this study, starch synthesized from cassava was converted into starch acetate via an esterification reaction. The drug-loaded nanoparticles were prepared using the nanoprecipitation method. Bergenin obtained from Flueggea leucopyrus leaves extract was used as the active ingredient for the encapsulation. The mean particle diameter of nanoparticles was 183 nm, determined by dynamic light scattering. Loading efficiency (LE%) and loading capacity (LC%) were determined by UV-Vis spectrum and showed clear absorption peaks at 217 nm and 273 nm specific for bergenin in the leaves extract. The LE% and LC% were 54.09% and 27.76% correspondingly. The drug release studies showed that acetylated starch nanoparticles allowed the immediate release of bergenin at pH 5.6. These results indicate that starch acetate nanoparticle is a promising vehicle for natural anticancer drugs and a potential candidate for targeted anticancer drug delivery.

Publications

Acetylated starch nanoparticles for encapsulation of Flueggea leucopyrus leaves extract for anticancer targeted drug delivery. At the 15th International Research Conference 2022, General Sir John Kotelawala Defence University, Sri Lanka.(Abstract)

Presentations

“Acetylated cassava starch nanoparticles for targeted anticancer drug delivery”,” Undergraduate Research Symposium ASURS 2022, 16th June 2022.

“Acetylated starch nanoparticles for encapsulation of Flueggea leucopyrus leaves extract for anticancer targeted drug delivery”, 15th International Research Conference, 30th September 2022

Skills

Research Skills

85%

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  • Information Retrieval: Adept at using research tools and databases to gather relevant information, whether it's academic literature, data, or other resources.
  • Critical Thinking: Ability to critically evaluate sources, assess the quality of information, and identify gaps in existing research.
  • Methodology: Understanding research methodologies, including quantitative and qualitative approaches, is essential for assisting with research design and data collection.

Data Analysis Skills

95%

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  • Statistical Analysis: Depending on the research project, proficiency in statistical analysis software (e.g., SPSS, R, or Python) may be required to analyze and interpret data.
  • Data Visualization: Being able to create clear and effective data visualizations (charts, graphs, etc.) to communicate research findings is valuable.
  • Database Management: Familiarity with database management systems and data organization is crucial for handling research data efficiently.

Communication Skills

90%

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  • Writing: Strong written communication skills are essential for drafting research reports, papers, and summaries. The ability to write clearly and concisely is particularly important.
  • Verbal CommunicationVerbal Communication: Effective verbal communication is necessary for presenting findings, discussing research progress, and collaborating with team members and researchers.
  • Interpersonal Skills: Building relationships and working well with colleagues, professors, and research subjects is vital for a positive research environment.

Time Management and Organization

85%

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  • Time Management: Research assistants often juggle multiple tasks and deadlines. Being able to prioritize and manage time efficiently is crucial.
  • Organization: Maintaining organized records, notes, and data is essential for tracking progress and ensuring that research materials are easily accessible.

Experience

Working Experience / Professional Training

Since 1st of May 2023

Research Assistant

Department of Food Technology, Faculty of Technology, Rajarata University of Sri Lanka

Project on extraction and characterization of dietary fibers from fruit and vegetable wastes generated in economic centers of Sri Lanka for potential food applications

11th of September 2021

Training Session

BAS Holdings Lanka (Pvt.) Ltd., online session

Quality Management

21st of Sep 2020 to Oct 9th

Industrial Training

GlaxoSmithKline PLC

Three weeks training at the chemical laboratory of the department of quality assurance.

2015 December to 2017 January

Medical Laboratory Technician

Asiri Hospital Holdings

Conducted blood tests including, blood sugar, cholesterol, liver profile, renal profile, and creatine